Friday, February 19, 2010
Is Dupuytren's an immune problem?
Is Dupuytren's an autoimmune or an allergic condition? In some fibrotic diseases, such as endomyocardial fibrosis, tissues show activity of eosinphils. Eosinophils are normally found in small numbers in the bloodstream. They are part of the immune system and are abnormally involved in some medical conditions such as asthma. Eosinophils are filled with little bags of chemicals, called granules, and in a prepared slide under the microscope, the granules stand out as beautiful little red jewels. Their pretty appearance is deceiving: some granules are filled with toxic compounds which are released to kill invading organisms. These toxins can also kill normal cells and cause scarring and fibrosis. Researchers analyzed tissue specimens for a possible link between eosinophils and fibrosis in several conditions, including Dupuytren's, and reported their findings in "Tissue Eosinophilia and Eosinophil Degranulation in Syndromes Associated with Fibrosis" (full text: http://www.dupuytrenfoundation.org/DupPDFs/1992_Noguchi_1104.pdf). They found strong evidence for eosinophil involvement in retroperitoneal fibrosis, sclerosing mediastinitis, and sclerosing cholangitis, but none in Dupuytren's. One less lead to investigate in the quest to find a cure for Dupuytren's.
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Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,Lupus,Lymne Disease,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Brain Tumor,Fibromyalgia,Fluoroquinolone Toxicity
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