Dupuytren Roundtable Discussions

Here are links to two recently published roundtable discussions by experts in the field of Dupuytren's. Although these were discussions by surgeons for surgeons, they are really just conversations and quite readable. They highlight the current challenges both surgeons and their patients face with Dupuytren's disease and provide insight into future efforts to develop a biological cure.

American Association of Hand Surgeons (go to page 6): http://www.dupuytrenfoundation.org/DupPDFs/2010_AAHS.pdf

American Academy of Orthopaedic Surgeons: http://www.dupuytrenfoundation.org/DupPDFs/2011_AAOS.pdf

Coming up: What is known about Dupuytren's and Chondroitin/Glucosamine?

Dupuytren Foundation 2010 Report

It's been a busy year behind the scenes for the Dupuytren Foundation - see what we've been up to at http://conta.cc/hV1lEy

Miami Dupuytren Symposium spurs new research: Report from Dupuytren's Day at the Deutsche Gesellschaft für Handchirurgiethe (German Society for Surgery of the Hand - DGH)

Dr Wolfgang Wach reports from the DGH, Oct 7 Dupuytren Program: "I attended the Dupuytren’s day at the Nuremberg conference of German hand surgeons and the Miami Dupuytren Symposium was pretty well covered there. Bernhard Lukas gave a review of the Miami conference and the current issue of the German hand surgeons journal which was distributed at the conference also contained a 3 page summary by Bernhard Lukas and Albrecht Meinel of the Miami conference. Lawrence Hurst presented collagenase. Albrecht Meinel presented an extended version of his Miami anatomy and his splinting papers, Bernhard Lukas presented his surgery paper, Holger Erne and Bernhard Lukas gave papers on NA, Ilse Degreef presented a summary of her papers, Hans Hennies presented an update on his genomics study and mentioned that, as result of the Miami Dupuytren Symposium, the UK, the Netherlands, and the German genomics study started cooperating and are exchanging samples. Great! I also gave a little patient talk.".
The full conference program can be downloaded at http://www.dgh-kongress.de/dgh2010/Hauptprogramm_DGH2010.pdf. The DGH web site is http://www.dg-h.de. This new joint effort of researchers is a realization of a goal of the Dupuytren Foundation: to spur global collaboration to develop better treatment options for Dupuytren's; to find a cure. It is happening.

Video: I was a Teenage Myofibroblast (and I loved it!)

Before becoming the villain in Dupuytren's, the myofibroblast was really not a bad cell. What happened? What caused the change? Could it happen to you? Professor Sem Phan, Department of Pathology, University of Michigan explains almost everything in this presentation of "Mechanisms of Myofibroblast Differentiation":
http://www.youtube.com/user/DupuytrenFoundation#p/u/0/dsPwSUDrz1Y

Funding for these and other Miami Dupuytren Symposium videos at http://dupuytrensymposium.com/program.html, is provided by the Dupuytren Foundation. Support the Dupuytren Foundation with an online donation: http://CureDup.com.

The Secret Life of Myofibroblasts: Dr. Boris Hinz reveals all!

Boris Hinz PhD, University of Toronto, Ontario, CA presents "Fundamental aspects of myofibroblast contraction." and explains how the process is both simple and complex. How do these little cells do such big things? More importantly, what steps in the process go wrong to result in Dupuytren's and what can be done to safely and simply correct this? Watch the video and see: http://www.youtube.com/user/DupuytrenFoundation#p/u/0/fvmRS3OiWic

Funding for these and other Miami Dupuytren Symposium videos at http://dupuytrensymposium.com/program.html, is provided by the Dupuytren Foundation. Support the Dupuytren Foundation with an online donation: http://CureDup.com.

Dupuytren's vs. Burns! Video: Dr. Paul Zidel at the 2010 Miami Dupuytren Symposium

Dr. Paul Zidel, Chief, Hand Surgery, Maricopa Medical Center, Phoenix, Arizona, presents a thought provoking comparison of two different yet similar conditions in "Dupuytren's versus burn scar contracture"
http://www.youtube.com/user/DupuytrenFoundation#p/u/0/uR5OcoIKfOI
Hypertrophic scars, Ledderhose disease, burn scars, keloid scars, desmoid tumors, pulmonary fibrosis, arteriosclerosis and other abnormal fibrosing conditions share some of the same complex biology as Dupuytren's. Answers found for one condition may apply to others - there are many stones yet unturned in the path to find a cure for Dupuytren's. Support the effort at http://CureDup.com

Dr. Paul Werker presents at the 2010 Dupuytren Symposium

Paul Werker MD PhD, Professor and Head of the Department of Plastic Surgery, Groningen University Medical Center Groningen, NL presents: Management of soft tissue contractures: a surgical perspective. See the video at http://www.youtube.com/user/DupuytrenFoundation#p/u/0/fHoOhGlsgDU. This and other video presentations from the 2010 International Symposium on Dupuytren's Disease, are being added to http://dupuytrensymposium.com/program.html. This symposium was made possible through funding from the Dupuytren Foundation. Join the effort to find a cure by making a donation to support research, education and global collaboration through the Dupuytren Foundation: http://CureDup.com.

Video: Dr. Osterman at the 2010 Miami Dupuytren Symposium

The latest installment of video presentations archived from the Miami Dupuytren Symposium features Dr. Lee Osterman, Professor of Hand/Orthopedic Surgery at the Thomas Jefferson University in Philadelphia, PA. Dr. Osterman's entertaining presentation highlights the complex background of efforts to understand and treat Dupuytren's Disease. See "Cline’s contracture: Dupuytren was a thief. A history of surgery for Dupuytren’s contracture." at http://www.youtube.com/user/DupuytrenFoundation#p/u/0/iOd0iZNbM_w. If you missed or had audio difficulties with previously posted symposium videos, check http://dupuytrensymposium.com/program.html for updated versions and new releases.